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SMAD5(C-term) Mouse Monoclonal Antibody
产品名称: SMAD5(C-term) Mouse Monoclonal Antibody
英文名称: SMAD5(C-term) Mouse Monoclonal Antibody
产品编号: K000033M
产品价格: null
产品产地: 北京市通州区马驹桥
品牌商标: solarbio
更新时间: 2025-02-08T13:37:52
使用范围: WB ICC FC
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
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- 邮箱 : 3193328036@qq.com
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Anti-SMAD5(C-term) Monoclonal Antibody
品牌:Solarbio | 货号:K000033M
英文名称 | Mouse SMAD5(C-term) Monoclonal Antibody |
---|---|
应用2 | WB FC ICC |
克隆类型2 | Monoclonal Antibody |
别名 | SMAD5(C-term) |
应用 | WB,ICC,FC |
稀释比例 | WB1:1000 ICC1:75 FCM1:100 |
交叉反应 | Human |
蛋白分子量 | 60kDa |
Gene ID | 4090 |
保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 52% Glycerol. |
纯化方法 | Affinity purification |
亚型 | IgG1 |
免疫原 | Purified recombinant human SMAD5 (C-terminus) protein fragments expressed in E.coli. |
性状 | Lyophilized or Liquid |
Swiss Prot | Q99717 |
克隆号 | 4B10-B10-B6 |
克隆类型 | Monoclonal Antibody |
来源 | Mouse |
背景资料 | SMAD5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. It is a receptor-regulated SMAD (R-SMAD), and acts as an intracellular signal transducer for the transforming growth factor beta superfamily. SMAD5 is activated through serine phosphorylation by BMP (bone morphogenetic proteins) type 1 receptor kinase. It is cytoplasmic in the absence of its ligand and migrates into the nucleus upon phosphorylation and complex formation with SMAD4. Here the SMAD5/SMAD4 complex stimulates the transcription of target genes. |